Effects of hyoscine-n-butylbromide on postoperative nausea and vomiting and postoperative pain in ureteroscopic procedures

Transdermal hyoscine and postoperative nausea and vomiting.

Forty-two patients, undergoing major gynaecological surgery, were randomly allocated to have a patch applied to the skin behind one ear, containing either hyoscine or placebo. They were followed up at 24-hour intervals for 3 days postoperatively and divided into matched pairs for statistical analysis. There was a significant (p less than 0.01) reduction in nausea and vomiting in the first 24 ho...

Transdermal Hyoscine and Postoperative Nausea and Vomiting

Sir,—Koski and colleagues [1] found no difference in the incidence of nausea and vomiting in patients receiving transdennal hyoscine or placebo before operation. This is at variance with the findings of others [2]. A number of points warrant mention. In the study of Koski, different types of surgery were performed, whereas only patients having gynaecological surgery were studied by Uppington, D...

Postoperative nausea and vomiting

Postoperative nausea and vomiting (PONV) is a long-standing issue, not a new concept in anesthesiology. Despite many studies over the last several decades, PONV remains a significant problem due to its complex mechanism. This review presents a summary of the mechanism underlying the pathogenesis of PONV, focusing on preventive treatment, particularly the use of new drugs. In addition, we discus...

Postoperative Nausea and Vomiting

Prophylactic Effect of Dexamethasone on Postoperative Nausea and Vomiting in Patients Undergoing Tympanomastoid Surgery

Postoperative nausea and vomiting is an unpleasant, distressing, and exhausting experience for patient. This is more common and severe in tympanomastoid surgery. The role of dexamethasone prevention of this complication is unclear and during recent years much attention has been paid to it. In order to evaluate prophylactic effect of dexamethasone on postoperative nausea and vomiting after masto...